Opioids are highly addictive and may end up in important adverse effects like life-threatening respiratory problems.  There's some proof of toddlers currently being born with neural tube defects (a dilemma with the spine as well as the nerves coming from the backbone) if codeine is used early in pregnancy and https://andersontbfim.angelinsblog.com/35247121/getting-my-delestrogen-40mg-mtf-to-work