Environmental or self-antigens and homotypic interactions result in BCR and Toll-like receptor (TLR) signaling, amplifying the reaction of CLL cells to other alerts from your microenvironment and rising the activation of anti-apoptotic and proliferation pathways.31,32 Genomic scientific studies have determined recurrent mutations in genes regulating tumor cell-microenvironment interac... https://elderg332ujz9.blogs100.com/profile